Clinical trialNCT07069738RecruitingInterventional

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

SponsorBoston Scientific CorporationEnrollment850Heart Failure - NYHA II - IV

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will compare two different methods to pace the heart to treat heart failure including: 1. The current standard method of implanting a pacing lead in a vein on the surface of the left lower chamber of the heart (left ventricle) to deliver heart failure therapy. This method is called Cardiac Resynchronization Therapy (CRT). 2. The other method is using a lead implanted in the Left Bundle Branch Area (LBBA) of your heart. This method is called Left Bundle Branch Area Pacing or LBBAP. This lead is approved by the Food and Drug Administration (FDA) to be implanted in this area of the heart, but not to provide heart failure treatment.

clinicaltrials.gov ↗

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

38 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Heart Center Research, Llc
Huntsville, Alabama, United States
John Jennings, Dr.
Recruiting
Mobile Infirmary Medical Center
Mobile, Alabama, United States
Ernest Matthew Quin, Dr.
Recruiting
Mayo Clinic Phoenix
Phoenix, Arizona, United States
Mayank Sardana, MD
Recruiting
Arrhythmia Research Group
Jonesboro, Arkansas, United States
Devi Nair, Dr.
Recruiting
Scripps Memorial Hospital
La Jolla, California, United States
Nicolas Olson, MD
Recruiting
Cedars Sinai Medical Center
Los Angeles, California, United States
Ashkan Ehdaie, MD
Recruiting
Alta Bates Summit Medical Center
Oakland, California, United States
Rajan Shah, Dr.
Recruiting
Pacific Heart Institute
Santa Monica, California, United States
Stephan Tang, MD
Recruiting
Torrance Medical Center
Torrance, California, United States
Gene Kim, MD
Recruiting
Cardiology Associates Medical Group, Inc.
Ventura, California, United States
Jonathan Dukes, Dr.
Recruiting
Washington Hospital Center
Washington D.C., District of Columbia, United States
Cyrus Hadadi, MD
Recruiting
Sarasota Memorial Hospital
Sarasota, Florida, United States
Antonio Moretta, Dr.
Recruiting
Adventhealth Tampa
Tampa, Florida, United States
Kenneth Yamamura, MD
Recruiting
Emory University Hospital
Atlanta, Georgia, United States
Anand Shah, MD
Recruiting
University of Chicago
Hinsdale, Illinois, United States
Shrinath Yeshwant, MD
Recruiting
Midwest Cardiovascular Institute
Naperville, Illinois, United States
Moeen Saleem, Dr.
Recruiting
Community Heart and Vascular Hospital
Indianapolis, Indiana, United States
Krishna Malineni, MD
Recruiting
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Paari Dominic, MD
Recruiting
Baptist Hospital East Louisville
Louisville, Kentucky, United States
Kevin Parrott, MD
Recruiting
Southcoast Physicians Group
Fall River, Massachusetts, United States
Arnoldas Giedrimas, MD
Recruiting
University of Michigan Hospitals
Ann Arbor, Michigan, United States
Thomas Crawford, MD
Recruiting
Corewell Health
Grand Rapids, Michigan, United States
Jawad Wassim, MD
Recruiting
St. Mary'S Duluth Clinic Regional Heart Center
Duluth, Minnesota, United States
Christopher Latanich, MD
Recruiting
Centracare Heart and Vascular Center
Saint Cloud, Minnesota, United States
Hardik Doshi, Dr.
Recruiting
Morristown Medical Center
Morristown, New Jersey, United States
Michael Katz, MD
Recruiting
Capital Cardiology Associates
Albany, New York, United States
Rizwan Alimohammad, MD
Recruiting
New York Hospital Queens
Flushing, New York, United States
Seth Goldbarg, Dr.
Recruiting
Rochester General Hospital
New York, New York, United States
Dmitry Chuprun, MD
Recruiting
Weill Cornell Medical University
New York, New York, United States
Jim Cheung, Dr.
Recruiting
Suny-Upstate Medical University
Syracuse, New York, United States
Jorge Romero, MD
Recruiting
Duke University Medical Center
Durham, North Carolina, United States
Daniel Friedman, MD
Recruiting
Mount Carmel Health System
Columbus, Ohio, United States
Kamel Addo, MD
Recruiting
Ohiohealth Research and Innovation Institute-Riverside Methodist Hospital
Columbus, Ohio, United States
Anish Amin, MD
Recruiting
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, United States
John Bullinga, MD
Recruiting
Avera Heart Hospital of South Dakota
Sioux Falls, South Dakota, United States
Christopher Stanton, Dr.
Recruiting
St.Thomas Health
Nashville, Tennessee, United States
Ricardo Lugo, MD
Recruiting
Heart Hospital Baylor Plano
Plano, Texas, United States
Mustafa Dohadwala, MD
Recruiting
Christus Trinity Mother Frances Health System
Tyler, Texas, United States
Stanislov Weiner, Dr.
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 22 Oct 2025
Primary completion: 30 Nov 2029
Completion: 30 Nov 2029
Last update posted: 4 Aug 2026
Registered enrollment: 850
Registry id: NCT07069738

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.