Clinical trialNCT05539196RecruitingObservational

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

SponsorInSightecEnrollment60Movement DisordersNeurologyParkinsons Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This registry is a prospective, multicenter, international, single arm, observational post-approval registry with follow-up at 3, 6, and 12 months, and annually for 5 years. The proposed registry will enroll 60 subjects and will be conducted at approximately 10 centers worldwide.

clinicaltrials.gov ↗

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Japan

Ohnishi Neurological Center
Akashi, Hyōgo, Japan
Yoshihiro Kuga, MD
Recruiting

United States

University of Maryland, Baltimore
Baltimore, Maryland, United States
Howard Eisenberg, MD
Recruiting
Weill Cornell Medicine
New York, New York, United States
Michael Kaplitt, MD PhD
Recruiting
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Casey Halpern, MD
Recruiting
University of Texas Southwestern Medical Center
Dallas, Texas, United States
Bhavya Shah, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 23 Jan 2023
Primary completion: 31 Jul 2029
Completion: 31 Jul 2029
Last update posted: 20 Mar 2026
Registered enrollment: 60
Registry id: NCT05539196

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.