Clinical trialNCT05564390RecruitingPhase 2Interventional

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

SponsorNational Cancer Institute (NCI)Enrollment2,000Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative NeoplasmAcute Myeloid Leukemia Post Cytotoxic TherapyAcute Myeloid Leukemia, Myelodysplasia-RelatedMyelodysplastic Syndrome

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This study involves testing patients' bone marrow and blood for certain biomarkers. A biomarker (sometimes called a marker) is any molecule in the body that can be measured. Doctors look at markers to learn what is happening in the body. Knowing about certain markers can give doctors more information about what is driving the cancer and how to treat it. Testing patients' bone marrow and blood will show doctors if patients have markers that specific drugs can target. The marker testing in this study will let doctors know if they can match patients with a treatment study (myeloMATCH clinical trial) that tests treatment for the type of cancer they have or continue standard of care treatment with their doctor on the Tier Advancement Pathway (TAP).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jerald P Radich
SWOG Cancer Research Network
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

348 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Arthur J E Child Comprehensive Cancer Centre
Calgary, Alberta, Canada
Mary L. Savoie
Recruiting
University of Alberta Hospital
Edmonton, Alberta, Canada
Joseph M. Brandwein
Recruiting
Cancercare Manitoba
Winnipeg, Manitoba, Canada
Brett L. Houston
Recruiting
Qeii Health Sciences Centre/nova Scotia Health Authority
Halifax, Nova Scotia, Canada
Mahmoud Elsawy
Recruiting
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, Canada
Alejandro Garcia-Horton
Recruiting
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Rena J. Buckstein
Recruiting
University Health Network-Princess Margaret Hospital
Toronto, Ontario, Canada
Guillaume Richard-Carpentier
Recruiting
Csss Champlain-Charles Le Moyne
Greenfield Park, Quebec, Canada
Sami Morin-Ben Abdallah
Recruiting
Ciusssemtl-Hopital Maisonneuve-Rosemont
Montreal, Quebec, Canada
Suspended
Jewish General Hospital
Montreal, Quebec, Canada
Sarit E. Assouline
Recruiting

Puerto Rico

Centro Comprensivo de Cancer de Upr
San Juan, Puerto Rico
Luis J. Santos Reyes
Recruiting
San Juan City Hospital
San Juan, Puerto Rico
Luis J. Santos Reyes
Recruiting

United States

University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States
Razan Mohty
Recruiting
Mayo Clinic Hospital in Arizona
Phoenix, Arizona, United States
James M. Foran
Recruiting
Banner University Medical Center - Tucson
Tucson, Arizona, United States
Sharad Khurana
Recruiting
University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States
Sharad Khurana
Recruiting
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Ankur Varma
Recruiting
Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California, United States
Active, not recruiting
Kaiser Permanente Dublin
Dublin, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente-Fremont
Fremont, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente Fresno Orchard Plaza
Fresno, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente-Fresno
Fresno, California, United States
Faisal N. Cheema
Recruiting
Uci Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, United States
Deepa Jeyakumar
Recruiting
Tibor Rubin Va Medical Center
Long Beach, California, United States
Active, not recruiting
Cedars-Sinai Medical Center
Los Angeles, California, United States
Noah M. Merin
Recruiting
Kaiser Permanente- Modesto Mob Ii
Modesto, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente-Modesto
Modesto, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente-Oakland
Oakland, California, United States
Faisal N. Cheema
Recruiting
Uc Irvine Health/chao Family Comprehensive Cancer Center
Orange, California, United States
Deepa Jeyakumar
Recruiting
Kaiser Permanente-Roseville
Roseville, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente Downtown Commons
Sacramento, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente-South Sacramento
Sacramento, California, United States
Faisal N. Cheema
Recruiting
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Brian A. Jonas
Recruiting
Kaiser Permanente-San Francisco
San Francisco, California, United States
Faisal N. Cheema
Recruiting
Ucsf Medical Center-Parnassus
San Francisco, California, United States
Timothy Ferng
Recruiting
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente San Leandro
San Leandro, California, United States
Faisal N. Cheema
Recruiting
Kaiser San Rafael-Gallinas
San Rafael, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, United States
Faisal N. Cheema
Recruiting
Kaiser Permanente-Santa Rosa
Santa Rosa, California, United States
Faisal N. Cheema
Recruiting

308 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Azacitidine →Busulfan →Cytarabine →Daunorubicin →Decitabine and CedazuridineEmavusertibEnasidenib →Epoetin alfa →Fludarabine →Gemtuzumab ozogamicin →Gilteritinib →Cpx-351Luspatercept →Melphalan →Olutasidenib →Placebo AdministrationVenetoclax →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 18 Jun 2024
Primary completion: 15 May 2029
Completion: 15 May 2029
Last update posted: 20 Aug 2026
Registered enrollment: 2,000
Registry id: NCT05564390

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.