Clinical trialNCT05649956RecruitingPhase 2Interventional

Letrozole in Uterine Leiomyosarcoma

SponsorGOG FoundationEnrollment40Uterine Leiomyosarcoma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Bradley Corr, MD
University of Colorado, Denver
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

34 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Colorado Cancer Center - Anschutz Cancer Pavilion
Aurora, Colorado, United States
Bradley Corr, MD
Recruiting
Highlands Ranch Hospital
Highlands Ranch, Colorado, United States
Bradley Corr, MD
Recruiting
Broward Health Medical Center
Fort Lauderdale, Florida, United States
Scott Jordan, MD
Recruiting
Mount Sinai Comprehensive Cancer Center
Miami Beach, Florida, United States
Brian Slomovitz, MD
Recruiting
Winship Cancer Institute, Emory Hospital
Atlanta, Georgia, United States
Susan Modesitt, MD
Recruiting
Endeavor Health - Kellogg Cancer Center
Evanston, Illinois, United States
Endeavor Health - Kellogg Cancer Center Jenkins-Vodel, MD
Recruiting
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana, United States
Lisa Landrum, MD
Recruiting
Lsu Health Sciences Center
New Orleans, Louisiana, United States
Tara Castellano, MD
Recruiting
Wk Physician Network-Gynecologic Oncology Associates
Shreveport, Louisiana, United States
Destin Black, MD
Recruiting
University of Massachusetts Memorial Medical Center
Worcester, Massachusetts, United States
Susan Zweizig, MD
Recruiting
Promedica Charles and Virginia Hickman Hospital,
Adrian, Michigan, United States
Anjalika Gandhi, MD, MS
Recruiting
Promedica Monroe Regional Hospital
Monroe, Michigan, United States
Anjalika Gandhi, MD, MS
Recruiting
University of Minnesota
Minneapolis, Minnesota, United States
Jordan Mattson, MD
Recruiting
Women'S Cancer Center of Nevada
Las Vegas, Nevada, United States
Nicola Spirtos, MD
Recruiting
Women'S Cancer Center of Nevada
Las Vegas, Nevada, United States
Peter Lim, MD
Recruiting
Atlantic Health System
Morristown, New Jersey, United States
Nana Tchabo, MD
Recruiting
Overlook Medical Center
Summit, New Jersey, United States
Nana Tchabo, MD
Recruiting
University of New Mexico Comprehensive Cancer Center
Albuquerque, New Mexico, United States
Carolyn Muller
Recruiting
East Carolina University Health Medical Center
Greenville, North Carolina, United States
Grainger Lanneau, MD
Recruiting
Ohiohealth Arthur G.H. Bing, Md Cancer Center
Columbus, Ohio, United States
Aine Clements, MD
Recruiting
Ohiohealth Grant Medical Center
Columbus, Ohio, United States
Aine Clements, MD
Recruiting
Ohiohealth Research Institute
Columbus, Ohio, United States
Aine Clements, MD
Recruiting
Ohiohealth Riverside Methodist Hospital
Columbus, Ohio, United States
Aine Clements, MD
Recruiting
Promedica Defiance Regional Hospital
Defiance, Ohio, United States
Anjalika Gandhi, MD, MS
Recruiting
Promedica Fostoria Community Hospital
Fostoria, Ohio, United States
Anjalika Gandhi, MD, MS
Recruiting
Promedica Memorial Hospital
Fremont, Ohio, United States
Anjalika Gandhi, MD, MS
Recruiting
Ohiohealth Marion General Hospital
Marion, Ohio, United States
Aine Clements, MD
Recruiting
Bay Park Hospital
Oregon, Ohio, United States
Anjalika Gandhi, MD, MS
Recruiting
Promedica Laboratories Perrysburg
Perrysburg, Ohio, United States
Anjalika Gandhi, MD, MS
Recruiting
Promedica Flower Hospital
Sylvania, Ohio, United States
Anjalika Gandhi, MD, MS
Recruiting
Promedica Toledo Hospital
Toledo, Ohio, United States
Anjalika Gandhi, MD, MS
Recruiting
University of Oklahoma Health Stephenson Cancer Center
Oklahoma City, Oklahoma, United States
Laura Holman, MD
Recruiting
Asplundh Cancer Pavilion
Willow Grove, Pennsylvania, United States
Tommy Buchanan, MD
Recruiting
Woman and Infants Hospital of Rhode Island
Providence, Rhode Island, United States
Matthew Oliver, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Letrozole →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 17 Jul 2024
Primary completion: 30 Jul 2028
Completion: 30 Jul 2029
Last update posted: 30 Jul 2026
Registered enrollment: 40
Registry id: NCT05649956

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.