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Clinical trialNCT05837455RecruitingPhase 2Interventional

NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast Cancer

SponsorWashington University School of MedicineEnrollment81Breast CancerCancer of the Breast
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study aims to utilize a novel biomarker-driven approach to guide neoadjuvant treatment selection. It is the hypothesis that this will improve clinical response for postmenopausal women with clinical stage II/III ER-positive, HER2-negative breast cancer and identify those who may not require neoadjuvant chemotherapy, with a primary focus on outcomes in Black patients.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Washington University School of Medicine

    St Louis, Missouri, United States

    Carolina Salvador, M.D.Cynthia X Ma, M.D., Ph.D.Debbie L Bennett, M.D.Emily L Podany, M.D.Fouad Boulos, M.D.Ian Hagemann, M.D., Ph.D.Jingqin (Rosy) Luo, Ph.D.John Olson, M.D., Ph.D.Katherine Glover-Collins, M.D., Ph.D.Katherine Weilbaecher, M.D.Nusayba A Bagegni, M.D.
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Anastrozole →Combination anthracycline and/or taxane based treatment
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 May 2024
Primary completion
30 Nov 2027
Completion
30 Nov 2027
Last update posted
13 Apr 2026
Registered enrollment
81
Registry id
NCT05837455
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.