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Clinical trialNCT07300475Not, yet, recruitingPhase 1Interventional

Personalized Cancer Vaccine (PCV) Strategy in Triple Negative Breast Cancer Patients

SponsorWashington University School of MedicineEnrollment30Triple Negative Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a phase 1 clinical trial to evaluate the safety, feasibility and immunogenicity of a personalized cancer vaccine (PCV) strategy with or without CD8-selective IL-2 mutein fusion protein in patients with triple negative breast cancer undergoing neoadjuvant chemoimmunotherapy.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Washington University School of Medicine

    St Louis, Missouri, United States

    Cynthia Ma, MD, PhDFeng Gao, MD, PhD, MPHIan Hagemann, MD, PhDKatherine Clifton, MDLijin Li, PhDMalachi Griffith, PhDObi Griffith, PhDPeter Goedegebuure, PhDRobert Schreiber, PhDSherri Davies, PhDWilliam Gillanders, MD

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AB248Carboplatin →Cyclophosphamide →Doxorubicin →Paclitaxel →Pembrolizumab →Personalized cancer vaccinePoly-ICLC
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Aug 2026
Primary completion
31 May 2030
Completion
30 Apr 2035
Last update posted
15 Jun 2026
Registered enrollment
30
Registry id
NCT07300475
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.