Clinical trialNCT06524544RecruitingPhase 3Interventional

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

SponsorNational Cancer Institute (NCI)Enrollment320Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaUnresectable Urothelial Carcinoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Monika Joshi
ECOG-ACRIN Cancer Research Group
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

152 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Cancer Center at Saint Joseph'S
Phoenix, Arizona, United States
Shahzad Siddique
Recruiting
Uci Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, United States
Nataliya Mar
Recruiting
Uc Irvine Health/chao Family Comprehensive Cancer Center
Orange, California, United States
Nataliya Mar
Recruiting
Uf Health Cancer Institute - Gainesville
Gainesville, Florida, United States
Daniel V. Araujo
Recruiting
Emory Saint Joseph'S Hospital
Atlanta, Georgia, United States
Jacqueline T. Brown
Recruiting
Emory University Hospital Midtown
Atlanta, Georgia, United States
Jacqueline T. Brown
Recruiting
Emory University Hospital/winship Cancer Institute
Atlanta, Georgia, United States
Jacqueline T. Brown
Recruiting
Kootenai Health - Coeur D'Alene
Coeur d'Alene, Idaho, United States
John M. Schallenkamp
Recruiting
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, United States
John M. Schallenkamp
Recruiting
Kootenai Clinic Cancer Services - Sandpoint
Sandpoint, Idaho, United States
John M. Schallenkamp
Recruiting
University of Illinois
Chicago, Illinois, United States
Karine Tawagi
Recruiting
Carle at the Riverfront
Danville, Illinois, United States
Priyank P. Patel
Recruiting
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, United States
Bryan A. Faller
Recruiting
Decatur Memorial Hospital
Decatur, Illinois, United States
Bryan A. Faller
Recruiting
Carle Physician Group-Effingham
Effingham, Illinois, United States
Priyank P. Patel
Recruiting
Crossroads Cancer Center
Effingham, Illinois, United States
Bryan A. Faller
Recruiting
Carle Physician Group-Mattoon/charleston
Mattoon, Illinois, United States
Priyank P. Patel
Recruiting
Carle Bromenn Medical Center
Normal, Illinois, United States
Priyank P. Patel
Recruiting
Carle Cancer Institute Normal
Normal, Illinois, United States
Priyank P. Patel
Recruiting
Cancer Care Center of O'Fallon
O'Fallon, Illinois, United States
Bryan A. Faller
Recruiting
Hshs Saint Elizabeth'S Hospital
O'Fallon, Illinois, United States
Bryan A. Faller
Recruiting
Memorial Hospital East
Shiloh, Illinois, United States
Melissa A. Reimers
Recruiting
Southern Illinois University School of Medicine
Springfield, Illinois, United States
Bryan A. Faller
Recruiting
Springfield Clinic
Springfield, Illinois, United States
Bryan A. Faller
Recruiting
Springfield Memorial Hospital
Springfield, Illinois, United States
Bryan A. Faller
Recruiting
Carle Cancer Center
Urbana, Illinois, United States
Priyank P. Patel
Recruiting
Mary Greeley Medical Center
Ames, Iowa, United States
Joseph J. Merchant
Recruiting
Mcfarland Clinic - Ames
Ames, Iowa, United States
Joseph J. Merchant
Recruiting
Mcfarland Clinic - Boone
Boone, Iowa, United States
Suspended
Mercy Hospital
Cedar Rapids, Iowa, United States
Deborah W. Wilbur
Recruiting
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, United States
Deborah W. Wilbur
Recruiting
Mcfarland Clinic - Trinity Cancer Center
Fort Dodge, Iowa, United States
Joseph J. Merchant
Recruiting
Mcfarland Clinic - Jefferson
Jefferson, Iowa, United States
Suspended
Mcfarland Clinic - Marshalltown
Marshalltown, Iowa, United States
Joseph J. Merchant
Recruiting
Haysmed
Hays, Kansas, United States
Saqib Abbasi
Recruiting
University of Kansas Cancer Center
Kansas City, Kansas, United States
Saqib Abbasi
Recruiting
the University of Kansas Cancer Center - Olathe
Olathe, Kansas, United States
Saqib Abbasi
Recruiting
University of Kansas Cancer Center-Overland Park
Overland Park, Kansas, United States
Saqib Abbasi
Recruiting
Salina Regional Health Center
Salina, Kansas, United States
Saqib Abbasi
Recruiting
University of Kansas Health System Saint Francis Campus
Topeka, Kansas, United States
Saqib Abbasi
Recruiting

112 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Carboplatin →Cisplatin →Docetaxel →Gemcitabine →Paclitaxel →Pembrolizumab →Sacituzumab →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 2 Dec 2025
Primary completion: 31 Dec 2028
Completion: 31 Dec 2028
Last update posted: 25 Jun 2026
Registered enrollment: 320
Registry id: NCT06524544

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.