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Clinical trialNCT06051695RecruitingPhase 1/PHASE2Interventional

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

SponsorA2 Biotherapeutics Inc.Enrollment474CRCCancerColon CancerColorectal AdenocarcinomaColorectal CancerLung Cancer+14 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Banner Health

    Gilbert, Arizona, United States

    Matthew Ulrickson, MD
    Recruiting
  • Ucsd Moores Cancer Center

    La Jolla, California, United States

    Sandip Patel, MD
    Recruiting
  • Ucla Medical Center

    Los Angeles, California, United States

    J. Randolph Hecht, MD
    Recruiting
  • Stanford University

    Stanford, California, United States

    Oliver Dorigo, MD
    Recruiting
  • Mayo Clinic

    Jacksonville, Florida, United States

    Yanyan Lou, MD
    Recruiting
  • Moffitt Cancer Center

    Tampa, Florida, United States

    Monica Avila, MD
    Recruiting
  • Mayo Clinic Rochester

    Rochester, Minnesota, United States

    Julian Molina, MD, PhD
    Recruiting
  • Washington University

    St Louis, Missouri, United States

    Jeffery Ward, MD
    Recruiting
  • Nyu Langone Medical Center

    New York, New York, United States

    Salman Punekar, MD
    Recruiting
  • the Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, United States

    Jinesh Gheeya, MD, PhD
    Recruiting
  • Vanderbilt University Medical Center

    Nashville, Tennessee, United States

    Cathy Eng, M.D., FACP, FASCO
    Recruiting
  • Fred Hutchinson Cancer Center

    Seattle, Washington, United States

    David Zhen, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
3 Apr 2024
Primary completion
30 Jun 2028
Completion
30 Jun 2029
Last update posted
12 Jun 2026
Registered enrollment
474
Registry id
NCT06051695

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.