Clinical trialNCT06112418RecruitingInterventional

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

SponsorCleerly, Inc.Enrollment7,500Diabetes Mellitus, Type 2Metabolic SyndromePreDiabetes

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

TRANSFORM is a prospective, randomized, open blinded endpoint (PROBE), event-driven, pragmatic trial in patients who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease. The trial tests the hypothesis that a Cleerly Coronary Artery Disease (CAD) Staging System-based care strategy reduces CV events compared with risk factor-based care.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

David J. Maron, MD, FASPC
Stanford University
Study ChairKOL profile →
clinicaltrials.gov ↗
Deepak Bhatt, MD, MPH
Mt. Sinai Heart
Study ChairKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

125 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Chandler Clinical Trials
Chandler, Arizona, United States
Recruiting
Scottsdale Clinical Trials
Scottsdale, Arizona, United States
Recruiting
Sun City Research
Sun City, Arizona, United States
Recruiting
Noble Clinical Research
Tucson, Arizona, United States
Recruiting
Amicis Research: Beverly Hills
Beverly Hills, California, United States
Recruiting
Cardiovascular Research Foundation of Southern California
Beverly Hills, California, United States
Recruiting
Valiance Clinical Research - Canoga Park
Canoga Park, California, United States
Recruiting
Cardiovascular Institute of San Diego
Chula Vista, California, United States
Recruiting
Amicis Research: Granada Hills
Granada Hills, California, United States
Recruiting
Valiance Clinical Research: Huntington Park
Huntington Park, California, United States
Recruiting
Halo Diagnostics
Indian Wells, California, United States
Recruiting
Scripps Health
La Jolla, California, United States
Recruiting
Chemidox Clinical Trials
Lancaster, California, United States
Recruiting
Loma Linda University Health
Loma Linda, California, United States
Recruiting
Long Beach Research Institute
Long Beach, California, United States
Recruiting
Ace Research Institute - Monterey Park
Monterey Park, California, United States
Recruiting
Amicis Research: Newhall
Newhall, California, United States
Recruiting
Ace Research Institute: Northridge
Northridge, California, United States
Recruiting
Ace Research Institute: Northridge #2
Northridge, California, United States
Recruiting
Amicis Research: Northridge
Northridge, California, United States
Recruiting
Northridge Clinical Trials
Northridge, California, United States
Active, not recruiting
University of California- Irvine
Orange, California, United States
Recruiting
Stanford Health Care
Palo Alto, California, United States
Recruiting
Va Palo Alto
Palo Alto, California, United States
Recruiting
Amicis Research: San Fernando
San Fernando, California, United States
Recruiting
Valiance Clinical Research - Tarzana
Tarzana, California, United States
Recruiting
Lundquist Institute for Biomedical Innovation at Harbor - Ucla Medical Center
Torrance, California, United States
Recruiting
Amicis Research: Valencia
Valencia, California, United States
Recruiting
Concierge Clinical Trials
Valley Village, California, United States
Recruiting
University of Colorado
Aurora, Colorado, United States
Steve Simon, MD
Recruiting
St. Josephs (intermountain Healthcare)
Denver, Colorado, United States
Recruiting
Flourish Medical Research
Boca Raton, Florida, United States
Recruiting
Apex Research
Cross City, Florida, United States
Recruiting
Evolution Research Center
Hialeah, Florida, United States
Recruiting
Uf Health Jacksonville
Jacksonville, Florida, United States
Recruiting
Atlantis Clinical Research, Llc
Miami, Florida, United States
Recruiting
Baptist Health Miami Cardiac and Vascular Institute
Miami, Florida, United States
Recruiting
Biophase Research
Miami, Florida, United States
Recruiting
Farma Medical Inc.
Miami, Florida, United States
Recruiting
Fiel Wellness Clinical Research Llc
Miami, Florida, United States
Recruiting

85 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 6 Mar 2024
Primary completion: 5 Mar 2029
Completion: 5 Mar 2029
Last update posted: 19 Aug 2026
Registered enrollment: 7,500
Registry id: NCT06112418

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.