Clinical trialNCT06230185RecruitingObservational

CtDNA Based MRD Testing for NAC Monitoring in TNBC

SponsorPersonalis Inc.Enrollment422Minimal Residual DiseaseTNBC - Triple-Negative Breast Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A prospective, multicenter, observational study to evaluate the correlation of Molecular Residual Disease (MRD) detection using circulating tumor DNA guided test to pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in stage I-III triple negative breast cancer (TNBC). Results from this study aim to improve MRD detection and disease outcomes for future patients.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Pavani Chalasani
George Washington University
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Arizona Oncology
Tucson, Arizona, United States
Recruiting
University of Colorado Cancer Center
Aurora, Colorado, United States
Recruiting
George Washington University
Washington D.C., District of Columbia, United States
Recruiting
Mount Sinai Medical Center of Florida
Miami Beach, Florida, United States
Recruiting
Comprehensive Hematology Oncology (onare Alliance, Llc / Exigent Research, Llc
St. Petersburg, Florida, United States
Recruiting
Illinois Cancer Care
Peoria, Illinois, United States
Recruiting
Louisiana State University
New Orleans, Louisiana, United States
Recruiting
Trinity Health-Michigan
Ypsilanti, Michigan, United States
Recruiting
Nebraska Methodist
Omaha, Nebraska, United States
Recruiting
Stony Brook University Cancer Center
Stony Brook, New York, United States
Recruiting
Oregon Oncology Specialists
Salem, Oregon, United States
Recruiting
Cancer Care Associates of York
York, Pennsylvania, United States
Recruiting
the University of Texas Md Anderson Cancer Center
Houston, Texas, United States
Recruiting
Cancer Care Northwest
Spokane, Washington, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 9 Nov 2023
Primary completion: 30 Aug 2025
Completion: 31 Dec 2025
Last update posted: 7 Jan 2025
Registered enrollment: 422
Registry id: NCT06230185

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.