Clinical trialNCT06527222RecruitingPhase 2Interventional

A Study of Ranolazine in ALS

SponsorSwathy Chandrashekhar, MBBSEnrollment72Amyotrophic Lateral Sclerosis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate safety, effect on cramps, function and quality of life of ranolazine versus placebo for the treatment of ALS.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jeffrey Statland, MD
University of Kansas Medical Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California, San Francisco
San Francisco, California, United States
Swathy Chandrashekhar, MD
Recruiting
Mayo Clinic Florida
Jacksonville, Florida, United States
Bjorn E Oskarsson, MD
Recruiting
University of Kansas Medical Center
Fairway, Kansas, United States
Jeffrey Statland, MD
Recruiting
University of Kansas Medical Center: Wichita
Wichita, Kansas, United States
Matthew Byerly, MD
Recruiting
University of Missouri Health Care
Columbia, Missouri, United States
William D Arnold, MD
Recruiting
the Ohio State University
Columbus, Ohio, United States
Sarah Heintzman, CNP
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboRanolazine →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 29 Apr 2025
Primary completion: 31 Jul 2028
Completion: 31 Jul 2028
Last update posted: 8 Jun 2026
Registered enrollment: 72
Registry id: NCT06527222

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.