Clinical trialNCT06665165RecruitingPhase 1Interventional

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

SponsorAmylyx Pharmaceuticals Inc.Enrollment48ALS

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Medical Director, Amylyx
Medical Monitor
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

University of Calgary
Calgary, Alberta, Canada
Collin Luk, MD, PhD
Recruiting
Mcmaster University
Hamilton, Ontario, Canada
Marvin Chum, MD
Recruiting
London Health Sciences Centre
London, Ontario, Canada
Christen Shoesmith, MD
Recruiting
Mcgill University Health Centre - Centre for Innovative Medicine
Montreal, Quebec, Canada
Angela Genge, MD
Recruiting

United States

University of California, San Diego
La Jolla, California, United States
John Ravits, MD
Recruiting
Georgetown University Hospital Pasquerilla Healthcare Center
Washington D.C., District of Columbia, United States
Shakti Nayar, MD
Recruiting
University of Florida
Gainesville, Florida, United States
James Wymer, MD, FAAN
Recruiting
Mayo Clinic in Florida
Jacksonville, Florida, United States
Bjorn Oskarsson, MD
Recruiting
Orlando Regional Medical Center, Orlando Health Neuroscience Institute
Orlando, Florida, United States
Vahid Tohidi, MD, PhD
Recruiting
Massachusetts General Hospital, Healey & Amg Center for Als
Boston, Massachusetts, United States
Sabrina Paganoni, MD, PhD
Recruiting
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Eric Sorenson, MD
Recruiting
Temple University of the Commonwealth System of Higher Education
Philadelphia, Pennsylvania, United States
Terry Heiman - Patterson, MD
Recruiting
Alliance for Multispecialty Research, Llc
Knoxville, Tennessee, United States
Randall Trudell, MD
Recruiting
Houston Methodist Neurological Institute
Houston, Texas, United States
Sheetal Shroff, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 7 Apr 2025
Primary completion: 28 Feb 2027
Completion: 31 Oct 2027
Last update posted: 14 Apr 2026
Registered enrollment: 48
Registry id: NCT06665165

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.