Clinical trialNCT06679270RecruitingPhase 3Interventional

Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

SponsorChiesi Farmaceutici S.p.A.Enrollment24Familial Partial Lipodystrophy

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This Phase 3 study is an Open Label Extension of the APG-20 Study To Evaluate the Long-term Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects with Partial Lipodystrophy

clinicaltrials.gov ↗

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama
Birmingham, Alabama, United States
Fernando Ovalle
Recruiting
Flourish Research
Boca Raton, Florida, United States
Rasha Youssef
Recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
Lindsay Fourman, MD
Recruiting
University of Michigan
Ann Arbour, Michigan, United States
Elif Oral, MD
Recruiting
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Vaneeta Bamba, MD
Recruiting
Ut Southwestern Medical Center
Dallas, Texas, United States
Abhimanyu Garg, MD
Recruiting
the Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Bradley Javorsky, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Metreleptin →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 14 Oct 2024
Primary completion: 31 Mar 2028
Completion: 31 Dec 2028
Last update posted: 16 Jul 2026
Registered enrollment: 24
Registry id: NCT06679270

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.