Clinical trialNCT06699121RecruitingPhase 2Interventional

A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSC

SponsorLISCure BiosciencesEnrollment87Primary Sclerosing Cholangitis (PSC)

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The study is designed to assess the safety and efficacy of LB-P8 in patients with primary sclerosing cholangitis.

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California Davis
Sacramento, California, United States
Christopher Bowlus, MD
Not, yet, recruiting
Uchealth University of Colorado Hospital
Aurora, Colorado, United States
Lisa Forman, MD
Not, yet, recruiting
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Alan Gunderson, MD
Recruiting
Mercy Medical Center
Baltimore, Maryland, United States
Paul Thuluvath, MD
Recruiting
Mayo Clinic
Rochester, Minnesota, United States
John Eton, MD
Not, yet, recruiting
the Vanderbilt Clinic
Nashville, Tennessee, United States
Manhal Izzy, MD
Recruiting
Liver Institute Northwest
Seattle, Washington, United States
Kris Kowdley, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

LB-P8 high-doseLB-P8 low-dosePlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Nov 2025
Primary completion: 31 Mar 2028
Completion: 28 Feb 2029
Last update posted: 24 Oct 2025
Registered enrollment: 87
Registry id: NCT06699121

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.