Clinical trialNCT06951217RecruitingPhase 2Interventional

An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

SponsorAvalyn Pharma Inc.Enrollment340Idiopathic Pulmonary Fibrosis (IPF)Progressive Pulmonary Fibrosis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is an open-label extension study for participants who were previously enrolled in and completed an Avalyn Pharma Sponsored study with an inhaled antifibrotic, such as AP01. Eligible participants will have their final dose of drug at the end of study visit from the lead-in study and first AP-LTE-008 study visit on the same day.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Avalyn Pharma, Inc.
Avalyn Pharma Inc.
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

68 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Argentina

Investigaciones En Patologias Respiratorias
San Miguel de Tucumán, Tucumán Province, Argentina
Ramon Angel Rosas
Recruiting
Cinme
Buenos Aires, Argentina
Maria Otaola
Recruiting
Fundación Respirar
Buenos Aires, Argentina
Pablo Doreski
Recruiting
Hospital Italiano de Buenos Aires
Buenos Aires, Argentina
Joaquin Maritano Furcada
Recruiting
Instituto Ave Pulmo, Fundacion Enfisema
Buenos Aires, Argentina
Luis Wehbe
Recruiting

Australia

Westmead Hospital
Westmead, New South Wales, Australia
John Wheatley
Recruiting
the Queen Elizabeth Hospital
Woodville South, South Australia, Australia
Active, not recruiting
Royal Prince Alfred Hospital
Camperdown, Australia
Tamera Corte
Recruiting
the Prince Charles Hospital (tpch)
Chermside, Australia
Peter Hopkins
Recruiting
Lung & Sleep Victoria
Footscray, Australia
Ian Glaspole
Recruiting
Respiratory Clinical Trials Pty Ltd
Kent Town, Australia
Michael Chia
Recruiting
Nepean Lung & Sleep
Kingston, Australia
Donald Lee
Recruiting
Univ of Western Australia / Institute for Respiratory Health
Nedlands, Australia
Vidya Navaratnam
Recruiting
John Hunter Hospital
New Lambton Heights, Australia
Christopher Grainge
Recruiting

Canada

Dynamic Drug Advancement
Ajax, Ontario, Canada
George Philteos
Recruiting
Research Institute Mcgill University Health Center
Montreal, Quebec, Canada
Deborah Assayag
Recruiting
Cic Mauricie
Trois-Rivières, Quebec, Canada
Emilie Millaire
Recruiting
Centre for Lung Health
Vancouver, Vancouver, Canada
Daniel Marinescu
Recruiting

Czechia

Fakultni Thomayerove Nemocnice
Praha Klanovice, Czechia
Martina Sterclova
Recruiting

France

University of Montpellier
Montrevel-en-Bresse, Montpellier, France
Arnaud Bourdin
Recruiting
Centre Hospitalier Universitaire D'Angers
Angers, France
Recruiting

Germany

Medizinische Hochschule Hannover
Hanover, Lower Saxony, Germany
Jonas Schupp
Recruiting
Studienzentrum Dr. Claus Keller
Frankfurt, Germany
Claus Keller
Recruiting

Italy

Fondazione Irccs Policlinico San Matteo - Uoc Pneumologia
Pavia, Lombardy, Italy
Recruiting
Humanitas Research Hospital
Milan, Italy
Francesco Amati
Recruiting
Ospedale San Giuseppe/ Multimedica Spa
Milan, Italy
Sergio Harari
Recruiting

Netherlands

St Antonius Hospital
Nieuwegein, Netherlands
Marcel Veltkamp
Recruiting

New Zealand

Greenlane Clinical Centre
Auckland, Auckland, New Zealand
Margaret Wilsher
Recruiting
Christchurch Hospital
Christchurch, Canterbury, New Zealand
Michael Epton
Recruiting
Bay of Plenty Clinical Trials Unit
Tauranga, Tauranga, New Zealand
Suzanne Poole
Recruiting
Dunedin Hospital
Dunedin, New Zealand
Active, not recruiting
Waikato Hospital
Hamilton, New Zealand
Catherina Chang
Recruiting

Poland

Uniwersyteckie Centrum Kliniczne
Gdansk, Poland
Recruiting
Department of Pneumology of the University Hospital No 1
Lodz, Poland
Recruiting

Spain

Hospital Universitario Virgen de Las Nieves
Granada, Andalusia, Spain
Ana Dolores Romero Ortiz
Recruiting
Hospital Gregorio Marañon
Madrid, Madrid, Spain
Luis Puente Maestu
Recruiting
Hospital Universitario Virgen de la Victoria
Málaga, Spain
Jose Luis Velasco Garrido
Recruiting

United Kingdom

Hull University Teaching Hospital
Cottingham, East Yorkshire, United Kingdom
Simon Hart
Recruiting
Ild Unit, University Hospitals Birmingham Nhs Foundation Trust Theme
Birmingham, West Midlands, United Kingdom
Anjali Crawshaw
Recruiting
Royal Papworth Hospital Nhs Foundation Trust
Cambridge, United Kingdom
Recruiting

28 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 17 Apr 2025
Primary completion: 31 Dec 2031
Completion: 31 Dec 2031
Last update posted: 7 Aug 2026
Registered enrollment: 340
Registry id: NCT06951217

Cross-registrations

ANZCTR (AU/NZ)ACTRN12625000246482

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.