Clinical trialNCT07051707RecruitingInterventional

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

SponsorNuvaira, Inc.Enrollment200COPDChronic Obstructive Pulmonary Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The dNerva Lung Denervation System is one-time treatment intended to improve breathing in Chronic Obstructive Pulmonary Disease (COPD) patients on standard medical care. The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System in the treatment of COPD.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Prof. Gerard Criner, MD
Temple Health
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama-Birmingham Hospital - Uab Lung Health Center
Birmingham, Alabama, United States
Surya Bhatt, MD
Recruiting
Mayo Clinic Jacksonville
Jacksonville, Florida, United States
Jose Soto Soto, MD
Recruiting
Henry Ford Hospital - Lung and Pulmonary Care
Detroit, Michigan, United States
Daniel Kapadia, MD
Recruiting
Wake Forest School of Medicine
Salem, North Carolina, United States
Jessica Bon, MD
Not, yet, recruiting
Ohio State University Medical Center - Ohio State Lung Center
Columbus, Ohio, United States
Christian Ghattas, MD
Recruiting
Penn Highlands - Lung Innovations/clinical Research Associates
DuBois, Pennsylvania, United States
Sandeep Bansai, MD
Recruiting
Temple University - Temple Lung Center
Philadelphia, Pennsylvania, United States
Gerard Criner, MD
Recruiting
University of Pittsburgh Medical Center - Umpc Comprehensive Lung Center
Pittsburgh, Pennsylvania, United States
Frank Sciurba, MD
Not, yet, recruiting
Virginia Commonwealth University Health System
Richmond, Virginia, United States
Ray (Wes) Shepherd, MD
Not, yet, recruiting
Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Johnathan Kurman, MD
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 24 Feb 2026
Primary completion: 30 Apr 2028
Completion: 31 Oct 2029
Last update posted: 28 Apr 2026
Registered enrollment: 200
Registry id: NCT07051707

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.