Clinical trialNCT07089121RecruitingPhase 1/PHASE2Interventional

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

SponsorCartesian TherapeuticsEnrollment50ANCA-Associated Vasculitis (AAV)Childhood-onset Systemic Lupus ErythematousJuvenile DermatomyositisJuvenile Myasthenia Gravis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Safety, tolerability and efficacy of Descarte-08 in children, adolescents and young adults with childhood-onset systemic lupus erythematosus, ANCA-associated vasculitis, juvenile myasthenia gravis, and juvenile dermatomyositis

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Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

H01- Children'S National Hospital
Washington D.C., District of Columbia, United States
Anant Vatsayan, MD
Recruiting
H03- Washington University School of Medicine
St Louis, Missouri, United States
Melissa Mavers, MD
Recruiting
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Hermine Brunner, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Descartes-08

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 14 Jan 2026
Primary completion: 31 Dec 2027
Completion: 31 Dec 2028
Last update posted: 27 Jul 2026
Registered enrollment: 50
Registry id: NCT07089121

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.