Clinical trialNCT07207876RecruitingObservational

Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

SponsorInternational Maternal Pediatric Adolescent AIDS Clinical Trials GroupEnrollment110Pregnancy

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

IMPAACT 2044 is a study to characterize the pharmacokinetics (PK) and safety of ceftriaxone and benzathine penicillin G during pregnancy. Up to 78 pregnant women receiving (1) ceftriaxone for indications other than syphilis or (2) benzathine penicillin G for treatment of syphilis from non-study clinical care providers will be enrolled at study sites located in the United States. Approximately 22 infants of pregnant participants receiving benzathine penicillin G will also be enrolled.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jason Zucker
Columbia Physicians & Surgeons (P&S) CRS
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

Site 5129, Impaact/gamma Project/upr Pediatric Hiv/aids Research Crs
San Juan, Puerto Rico
Recruiting

United States

Site 5048, Usc - Maternal Child Adolescent/adult Center
Los Angeles, California, United States
Recruiting
Site 5112, David Geffen School of Medicine at Ucla Nichd Crs
Los Angeles, California, United States
Recruiting
Site 4001, Lurie Children'S Hospital of Chicago (lch) Crs
Chicago, Illinois, United States
Recruiting
Site 5083, Rush Univ. Cook County Hosp. Chicago Nichd Crs
Chicago, Illinois, United States
Not, yet, recruiting
Site 5040, Suny Stony Brook Nichd Crs
Stony Brook, New York, United States
Recruiting
Site 5013, Jacobi Med. Ctr. Bronx Nichd Crs
The Bronx, New York, United States
Recruiting
Site 5114, Bronx-Lebanon Hospital Center Nichd Crs
The Bronx, New York, United States
Recruiting
Site 5128, Baylor College of Medicine/texas Children'S Hospital Nichd Crs
Houston, Texas, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Penicillin G →Ceftriaxon

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 16 Feb 2026
Primary completion: 15 Jan 2027
Completion: 30 Sept 2027
Last update posted: 6 Aug 2026
Registered enrollment: 110
Registry id: NCT07207876

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.