Clinical trialNCT07222137RecruitingPhase 3Interventional

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

SponsorEli Lilly and CompanyEnrollment150Diabetes Mellitus, Type 1

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to find out if baricitinib can delay the onset of clinical type 1 diabetes (T1D) in people who are at high risk to develop T1D. Participation in the study will last up to approximately 5 years.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST)
Eli Lilly and Company
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

111 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Women'S and Children'S Hospital
Adelaide, Australia
Jennifer Couper
Recruiting
Box Hill Hospital
Box Hill, Australia
Ming Li Yee
Recruiting
Centre for Children'S Health Research
Brisbane, Australia
Tony Huynh
Recruiting
Royal Brisbane and Women'S Hospital
Brisbane, Australia
Donald McLeod
Recruiting
Royal Children'S Hospital
Melbourne, Australia
Fergus Cameron
Not, yet, recruiting
the Royal Melbourne Hospital
Parkville, Australia
John Wentworth
Recruiting
Perth Children'S Hospital
Perth, Australia
Elizabeth Davis
Recruiting
Sydney Children'S Hospital
Randwick, Australia
Kristen Neville
Recruiting
the Children'S Hospital at Westmead
Westmead, Australia
Ann Maguire
Recruiting

Belgium

Cliniques Universitaires Saint-Luc
Brussels, Belgium
Philippe Lysy
Not, yet, recruiting
Uz Brussel
Brussels, Belgium
Willem Staels
Not, yet, recruiting
Antwerp University Hospital
Edegem, Belgium
Christophe De Block
Not, yet, recruiting
Uz Leuven
Leuven, Belgium
Chantal Mathieu
Recruiting
Chu Ucl Namur/site Sainte Elisabeth
Namur, Belgium
Dominique Beckers
Not, yet, recruiting

Brazil

Freire Pesquisa Clínica
Belo Horizonte, Brazil
Flávia Maia
Recruiting
Centro de Diabetes Curitiba
Curitiba, Brazil
André Vianna
Recruiting
Hospital Universitario Walter Cantidio
Fortaleza, Brazil
Renan Montenegro
Recruiting
Cendi - Endocrinologia E Diabetes
Goiânia, Brazil
Nelson Rassi
Recruiting
Centro de Pesquisa Clínica de Marília - Cpclim
Marília, Brazil
José Sgarbi
Recruiting
Universidade Federal Do Rio de Janeiro
Rio de Janeiro, Brazil
Melanie Rodacki
Recruiting
Cpclin
São Paulo, Brazil
Denise Franco
Recruiting
Hospital Das Clinicas Fmusp
São Paulo, Brazil
Maria Elizabeth Rossi da Silva
Recruiting
Ibted - Tecnologia E Educação Em Diabetes
São Paulo, Brazil
Monica Gabbay
Recruiting
Instituto de Pesquisa Clinica
São Paulo, Brazil
Joao Salles
Recruiting

Canada

Alberta Children'S Hospital
Calgary, Canada
Carol Huang
Not, yet, recruiting
Alberta Diabetes Institute
Edmonton, Canada
Peter Senior
Not, yet, recruiting
Bc Diabetes Office
Vancouver, Canada
Thomas Elliott
Recruiting

Finland

Oulun Yliopistollinen Sairaala
Oulu, Finland
Riitta Veijola
Recruiting
Tampereen Yliopistollinen Sairaala
Tampere, Finland
Sauli Palmu
Recruiting
Turku University Hospital
Turku, Finland
Jorma Toppari
Recruiting

France

Hospices Civils de Lyon - Hopital Louis Pradel
Bron, France
Marc Nicolino
Not, yet, recruiting
Centre Hospitalier Sud Francilien
Corbeil-Essonnes, France
Alfred Penfornis
Not, yet, recruiting
Hopital Claude Huriez - Chu de Lille
Lille, France
Anne VAMBERGUE
Not, yet, recruiting
Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone
Marseille, France
Rachel Reynaud
Not, yet, recruiting
Assistance Publique - Hopitaux de Paris (ap-Hp) - Hopital Robert Debre - Centre Hospitalo Universitaire (c -T
Paris, France
Elise Bismuth
Not, yet, recruiting
Hopitaux Universitaires Paris Centre-Hopital Cochin
Paris, France
Roberto Mallone
Not, yet, recruiting
Hôpital Universitaire Necker Enfants Malades
Paris, France
Alix BESANCON
Not, yet, recruiting
Pitie Salpetriere University Hospital
Paris, France
Chloé AMOUYAL
Not, yet, recruiting
Chu Rangueil
Toulouse, France
Pierre Gourdy
Not, yet, recruiting

Germany

Klinik Josefinum
Augsburg, Germany
Thomas Völkl
Not, yet, recruiting

71 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

BaricitinibPlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 12 Jan 2026
Primary completion: 31 Jul 2031
Completion: 31 Jul 2031
Last update posted: 6 Aug 2026
Registered enrollment: 150
Registry id: NCT07222137

Cross-registrations

EU-CTR / CTIS (EudraCT)2025-521797-34-00

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.