Clinical trialNCT07222332RecruitingPhase 3Interventional

A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

SponsorEli Lilly and CompanyEnrollment300Diabetes Mellitus, Type 1

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to find out if baricitinib can preserve beta-cell function in participants newly diagnosed with type 1 diabetes. Participation in the study will last about 60 weeks.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST)
Eli Lilly and Company
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

138 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Women'S and Children'S Hospital
Adelaide, Australia
Jennifer Couper
Recruiting
Centre for Children'S Health Research
Brisbane, Australia
Tony Huynh
Not, yet, recruiting
Austin Health - Repatriation Hospital
Heidelberg West, Australia
Elif Ekinci
Recruiting
Ipswich Hospital
Ipswich, Australia
Thomas Dover
Recruiting
Royal Children'S Hospital
Melbourne, Australia
Fergus Cameron
Not, yet, recruiting
Southern Adelaide Diabetes & Endocrine Services
Oaklands Park, Australia
Natalie Giles
Recruiting
the Royal Melbourne Hospital
Parkville, Australia
John Wentworth
Recruiting
Perth Children'S Hospital
Perth, Australia
Elizabeth Davis
Recruiting
Sydney Children'S Hospital
Randwick, Australia
Kristen Neville
Recruiting
the Children'S Hospital at Westmead
Westmead, Australia
Ann Maguire
Recruiting

Belgium

Cliniques Universitaires Saint-Luc
Brussels, Belgium
Philippe Lysy
Not, yet, recruiting
Uz Brussel
Brussels, Belgium
Willem Staels
Not, yet, recruiting
Université Libre de Bruxelles - Hôpital Erasme
Brussels, Belgium
Miriam Cnop
Not, yet, recruiting
Antwerp University Hospital
Edegem, Belgium
Christophe De Block
Not, yet, recruiting
Uz Gent
Ghent, Belgium
Imke Matthys
Recruiting
Uz Leuven
Leuven, Belgium
Chantal Mathieu
Recruiting
Centre Hospitalier Universitaire de Liège - Domaine Universitaire Du Sart Tilman
Liège, Belgium
jean-christophe philips
Not, yet, recruiting
Chu Ucl Namur/site Sainte Elisabeth
Namur, Belgium
Dominique Beckers
Not, yet, recruiting
Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godinne
Yvoir, Belgium
Dominique Beckers
Not, yet, recruiting

Brazil

Hospital Universitário Maria Aparecida Pedrossian
Campo Grande, Brazil
Delcio da Silva Junior
Recruiting
Centro de Diabetes Curitiba
Curitiba, Brazil
André Vianna
Recruiting
Quanta Diagnóstico E Terapia
Curitiba, Brazil
Rosangela Rea
Recruiting
Centro de Diabetes Metabolismo E Endocrinologia
Fortaleza, Brazil
ADRIANA FORTI
Recruiting
Cendi - Endocrinologia E Diabetes
Goiânia, Brazil
Nelson Rassi
Recruiting
Centro de Pesquisa Clínica de Marília - Cpclim
Marília, Brazil
José Sgarbi
Recruiting
Instituto Da Crianca Com Diabetes
Porto Alegre, Brazil
Balduino Tschiedel
Recruiting
Hospital Das Clínicas Da Faculdade de Medicina de Ribeirão Preto Da Universidade de São Paulo (usp) - Hcfm -T
Ribeirão Preto, Brazil
Raphael Liberatore
Recruiting
Universidade Federal Do Rio de Janeiro
Rio de Janeiro, Brazil
Melanie Rodacki
Recruiting
Cpclin
São Paulo, Brazil
Denise Franco
Recruiting
Clínica Hepatogastro Jk
São Paulo, Brazil
DEBORA NAZATO
Recruiting
Hospital Das Clinicas Fmusp
São Paulo, Brazil
Maria Elizabeth Rossi da Silva
Recruiting
Ibted - Tecnologia E Educação Em Diabetes
São Paulo, Brazil
Monica Gabbay
Recruiting
Instituto de Pesquisa Clinica
São Paulo, Brazil
Joao Salles
Recruiting
Cedoes
Vitória, Brazil
Queulla Santos
Recruiting

Canada

Alberta Children'S Hospital
Calgary, Canada
Carol Huang
Not, yet, recruiting
Ciusss- Saguenay-Lac-Saint-Jean
Chicoutimi, Canada
Raphaëlle Chrétien
Recruiting
Alberta Diabetes Institute
Edmonton, Canada
Peter Senior
Not, yet, recruiting
St. Joseph'S Health Care
London, Canada
Tamara Spaic
Not, yet, recruiting
Centricity Research Ottawa Lmc Endocrinology
Ottawa, Canada
Nadia Malakieh
Recruiting
Chul Et Centre Mère-Enfant Soleil
Québec, Canada
Martin D'Amours
Not, yet, recruiting

98 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

BaricitinibPlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 5 Feb 2026
Primary completion: 31 Jul 2028
Completion: 31 Jul 2028
Last update posted: 21 Aug 2026
Registered enrollment: 300
Registry id: NCT07222332

Cross-registrations

EU-CTR / CTIS (EudraCT)2025-522170-36-00

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.