Clinical trialNCT07430917Not, yet, recruitingPhase 2Interventional

Safety and Efficacy of J147 in Acute Ischemic Stroke

SponsorAbrexa Pharmaceuticals, Inc.Enrollment196Acute Ischemic Stroke

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this clinical trial is to find out if the drug J147 improves outcomes for persons who have had an ischemic stroke. It also will learn about the safety of J147 when given by injection to stroke patients. Researchers will compare the outcomes of those who receive J147 after therapy to clear the blood clot to those who don't receive J147. Participants will be asked to undergo a series of three to four magnetic resonance imaging (MRI) brain scans, and blood samples will be collected at several time points. Participants will also be evaluated to measure several aspects of brain function.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Marguerite Prior, Ph.D.
Abrexa Pharmaceuticals, Inc.
Study Director
clinicaltrials.gov ↗
Steven J Warach, MD, PhD
Dell Seton Medical Center at the University of Texas at Austin
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Dell Seton Medical Center at the University of Texas at Austin
Austin, Texas, United States
Borna Tabibian, MDElham Askari, MDHamidreza Saber, MDJefferson Miley, MDLisa Davis, PhD, RNManzure Mawla, DOMatthew Padrick, MDRachel Pearson, MDSteven J Warach, MD, PhD →Supreet Kaur, MDZachary Brittingham, DO

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

J147 Emulsion for Injection

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 Apr 2026
Primary completion: 1 Mar 2028
Completion: 1 Jul 2028
Last update posted: 7 Apr 2026
Registered enrollment: 196
Registry id: NCT07430917

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.