Clinical trialNCT07579429RecruitingPhase 2Interventional

Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial)

SponsorUniversity of Colorado, DenverEnrollment10Clonal Cytopenia of Undetermined SignificanceMyelodysplastic Syndrome

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is an open-label, phase 2 study for lower risk MDS and high risk CCUS patients who are transfusion independent. There will be two cohorts enrolled at the same time to measure the effect of nicotinamide riboside and pterostilbene at different doses. The primary goals of the study are: * to assess if study drug improves cytopenias in patients * to determine safety of the study drug in patients

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Maria Amaya, PhD MD
University of Colorado, Denver
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Colorado Hospital
Aurora, Colorado, United States
Ajay Major, MDAndrew Kent, MDBradley Haverkos, MDCassandra Duarte, MDChristine McMahon, MDDaniel Pollyea, MDDaniel Sherbenou, MDJonathan Gutman, MDJorge Monge-Urrea, MDManali Kamdar, MDMaria Amaya, PhD MDMatthew Angelos, MDSteven Bair, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Nicotinamide RibosidePterostilbene

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 May 2026
Primary completion: 18 Dec 2029
Completion: 18 Dec 2030
Last update posted: 3 Jun 2026
Registered enrollment: 10
Registry id: NCT07579429

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.