Clinical trialNCT01658514CompletedPhase 2Interventional

Assessing the Behavior of Met DR in Subjects With Kidney Dysfunction

SponsorElcelyx Therapeutics, Inc.Enrollment39Renal Insufficiency

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study evaluated how a single dose of delayed-release metformin (Met DR) behaves in subjects with normal kidney function, mild kidney dysfunction, moderate kidney dysfunction, or severe kidney dysfunction. The safety and tolerability of Met DR was also examined. In addition, this study compared the behavior of a single dose of Met DR with that of extended-release metformin (Met XR) and placebo in subjects with the varying levels of kidney function described above.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alexander White, MD
Progressive Medical Research
Principal Investigator
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Craig Curtis, MD
Compass Research
Principal Investigator
clinicaltrials.gov ↗
George Canas, MD
Prism Research
Principal Investigator
clinicaltrials.gov ↗
Harold Bays, MD
Louisville Metabolic and Atherosclerosis Research Center
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Kenneth Lasseter, MD
Clinical Pharmacology of Miami, Inc
Principal Investigator
clinicaltrials.gov ↗
Nelson Kopyt
Northeast Clinical Research Center
Principal Investigator
clinicaltrials.gov ↗
Prabir Roy-Chaudhury
Cincinnati Veterans Affairs Medical Center Department of Internal Medicine
Principal Investigator
clinicaltrials.gov ↗
Sunder Mudaliar
San Diego Veterans Healthcare System
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Met DRMet XRPlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jan 2014
Primary completion: 30 Jun 2014
Completion: 30 Jun 2014
Last update posted: 30 Dec 2015
Registered enrollment: 39
Registry id: NCT01658514

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.