Clinical trialNCT04181060RecruitingPhase 3Interventional

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

SponsorNational Cancer Institute (NCI)Enrollment300Advanced Lung Non-Squamous Non-Small Cell CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaRecurrent Lung Non-Squamous Non-Small Cell CarcinomaStage IIIB Lung Cancer AJCC v8Stage IV Lung Cancer AJCC v8

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Helena A Yu
ECOG-ACRIN Cancer Research Group
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

603 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Alaska Breast Care and Surgery Llc
Anchorage, Alaska, United States
Suspended
Alaska Oncology and Hematology Llc
Anchorage, Alaska, United States
Alison K. Conlin
Recruiting
Alaska Women'S Cancer Care
Anchorage, Alaska, United States
Suspended
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, United States
Suspended
Anchorage Oncology Centre
Anchorage, Alaska, United States
Suspended
Anchorage Radiation Therapy Center
Anchorage, Alaska, United States
Suspended
Katmai Oncology Group
Anchorage, Alaska, United States
Alison K. Conlin
Recruiting
Providence Alaska Medical Center
Anchorage, Alaska, United States
Suspended
Fairbanks Memorial Hospital
Fairbanks, Alaska, United States
John M. Schallenkamp
Recruiting
Cancer Center at Saint Joseph'S
Phoenix, Arizona, United States
Shahzad Siddique
Recruiting
Mercy Hospital Fort Smith
Fort Smith, Arkansas, United States
Suspended
Chi Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas, United States
Suspended
Nea Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro, Arkansas, United States
Philip E. Lammers
Recruiting
Kaiser Permanente-Deer Valley Medical Center
Antioch, California, United States
Jennifer M. Suga
Recruiting
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California, United States
Suspended
Providence Saint Joseph Medical Center/disney Family Cancer Center
Burbank, California, United States
Suspended
Kaiser Permanente Dublin
Dublin, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Fremont
Fremont, California, United States
Jennifer M. Suga
Recruiting
Washington Hospital
Fremont, California, United States
Bogdan S. Eftimie
Recruiting
Kaiser Permanente Fresno Orchard Plaza
Fresno, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Fresno
Fresno, California, United States
Jennifer M. Suga
Recruiting
Uc San Diego Moores Cancer Center
La Jolla, California, United States
Withdrawn
Kaiser Permanente- Modesto Mob Ii
Modesto, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Modesto
Modesto, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Oakland
Oakland, California, United States
Jennifer M. Suga
Recruiting
Stanford Cancer Institute Palo Alto
Palo Alto, California, United States
Joel W. Neal
Recruiting
Kaiser Permanente-Richmond
Richmond, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Roseville
Roseville, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente Downtown Commons
Sacramento, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-South Sacramento
Sacramento, California, United States
Jennifer M. Suga
Recruiting
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Surbhi Singhal
Recruiting
Salinas Valley Memorial
Salinas, California, United States
Active, not recruiting
Kaiser Permanente-San Francisco
San Francisco, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente San Leandro
San Leandro, California, United States
Jennifer M. Suga
Recruiting
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California, United States
Suspended
Kaiser San Rafael-Gallinas
San Rafael, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, United States
Jennifer M. Suga
Recruiting
Mission Hope Medical Oncology - Santa Maria
Santa Maria, California, United States
Suspended
Kaiser Permanente-Santa Rosa
Santa Rosa, California, United States
Jennifer M. Suga
Recruiting

563 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 28 Dec 2020
Primary completion: 31 Dec 2026
Completion: 31 Dec 2026
Last update posted: 9 Jul 2026
Registered enrollment: 300
Registry id: NCT04181060

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.