Clinical trialNCT04628767RecruitingPhase 2/PHASE3Interventional

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

SponsorNational Cancer Institute (NCI)Enrollment131Renal Pelvis and Ureter Urothelial Carcinoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jean H Hoffman-Censits
ECOG-ACRIN Cancer Research Group
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

258 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Kingman Regional Medical Center
Kingman, Arizona, United States
John A. Ellerton
Recruiting
Mercy Hospital Fort Smith
Fort Smith, Arkansas, United States
Suspended
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Active, not recruiting
Sutter Auburn Faith Hospital
Auburn, California, United States
Active, not recruiting
Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California, United States
Active, not recruiting
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Abhishek Tripathi
Recruiting
Palo Alto Medical Foundation-Fremont
Fremont, California, United States
Active, not recruiting
Uc San Diego Moores Cancer Center
La Jolla, California, United States
Aditya Bagrodia
Recruiting
Memorial Medical Center
Modesto, California, United States
Active, not recruiting
Palo Alto Medical Foundation-Camino Division
Mountain View, California, United States
Active, not recruiting
Palo Alto Medical Foundation Health Care
Palo Alto, California, United States
Active, not recruiting
Stanford Cancer Institute Palo Alto
Palo Alto, California, United States
Ali R. Khaki
Recruiting
Sutter Roseville Medical Center
Roseville, California, United States
Active, not recruiting
Sutter Medical Center Sacramento
Sacramento, California, United States
Active, not recruiting
Uc San Diego Medical Center - Hillcrest
San Diego, California, United States
Aditya Bagrodia
Recruiting
California Pacific Medical Center-Pacific Campus
San Francisco, California, United States
Active, not recruiting
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California, United States
Active, not recruiting
Sutter Pacific Medical Foundation
Santa Rosa, California, United States
Active, not recruiting
Palo Alto Medical Foundation-Sunnyvale
Sunnyvale, California, United States
Active, not recruiting
Sutter Solano Medical Center/cancer Center
Vallejo, California, United States
Active, not recruiting
Uchealth University of Colorado Hospital
Aurora, Colorado, United States
Elizabeth R. Kessler
Recruiting
Uchealth - Cherry Creek
Denver, Colorado, United States
Suspended
Cancer Care and Hematology-Fort Collins
Fort Collins, Colorado, United States
Elizabeth R. Kessler
Recruiting
Poudre Valley Hospital
Fort Collins, Colorado, United States
Elizabeth R. Kessler
Recruiting
Uchealth Greeley Hospital
Greeley, Colorado, United States
Elizabeth R. Kessler
Recruiting
Uchealth Highlands Ranch Hospital
Highlands Ranch, Colorado, United States
Elizabeth R. Kessler
Recruiting
Uchealth Lone Tree Health Center
Lone Tree, Colorado, United States
Elizabeth R. Kessler
Recruiting
Medical Center of the Rockies
Loveland, Colorado, United States
Elizabeth R. Kessler
Recruiting
Medstar Washington Hospital Center
Washington D.C., District of Columbia, United States
Suthee Rapisuwon
Recruiting
Sibley Memorial Hospital
Washington D.C., District of Columbia, United States
Jean H. Hoffman-Censits
Recruiting
Mayo Clinic in Florida
Jacksonville, Florida, United States
Active, not recruiting
Emory Saint Joseph'S Hospital
Atlanta, Georgia, United States
Jacqueline T. Brown
Recruiting
Emory University Hospital Midtown
Atlanta, Georgia, United States
Jacqueline T. Brown
Recruiting
Emory University Hospital/winship Cancer Institute
Atlanta, Georgia, United States
Jacqueline T. Brown
Recruiting
Emory Decatur Hospital
Decatur, Georgia, United States
Jacqueline T. Brown
Recruiting
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho, United States
Elie G. Dib
Recruiting
Osf Saint Anthony'S Health Center
Alton, Illinois, United States
Suspended
Advocate Good Shepherd Hospital
Barrington, Illinois, United States
Thomas J. Saphner
Recruiting
Illinois Cancercare-Bloomington
Bloomington, Illinois, United States
Active, not recruiting
Loyola Center for Health at Burr Ridge
Burr Ridge, Illinois, United States
Active, not recruiting

218 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Cisplatin →Doxorubicin →Durvalumab →Gemcitabine →Methotrexate →Pegfilgrastim →Vinblastine

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 12 Nov 2021
Primary completion: 30 Sept 2027
Completion: 30 Sept 2027
Last update posted: 8 Jul 2026
Registered enrollment: 131
Registry id: NCT04628767

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.