Clinical trialNCT05408845RecruitingPhase 2Interventional

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

SponsorNRG OncologyEnrollment146Metastatic Salivary Gland CarcinomaRecurrent Salivary Gland CarcinomaStage III Major Salivary Gland Cancer AJCC v8Stage IV Major Salivary Gland Cancer AJCC v8Unresectable Salivary Gland Carcinoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alan L Ho
NRG Oncology
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

152 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States
Active, not recruiting
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Active, not recruiting
Kaiser Permanente Dublin
Dublin, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Fremont
Fremont, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente Fresno Orchard Plaza
Fresno, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Fresno
Fresno, California, United States
Jennifer M. Suga
Recruiting
City of Hope at Irvine Lennar
Irvine, California, United States
Active, not recruiting
Kaiser Permanente- Modesto Mob Ii
Modesto, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Modesto
Modesto, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Oakland
Oakland, California, United States
Jennifer M. Suga
Recruiting
Stanford Cancer Institute Palo Alto
Palo Alto, California, United States
Alexander D. Colevas
Recruiting
Kaiser Permanente-Roseville
Roseville, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente Downtown Commons
Sacramento, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-South Sacramento
Sacramento, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-San Francisco
San Francisco, California, United States
Jennifer M. Suga
Recruiting
Ucsf Medical Center-Mission Bay
San Francisco, California, United States
Suspended
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente San Leandro
San Leandro, California, United States
Jennifer M. Suga
Recruiting
Kaiser San Rafael-Gallinas
San Rafael, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Santa Rosa
Santa Rosa, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-South San Francisco
South San Francisco, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Vallejo
Vallejo, California, United States
Jennifer M. Suga
Recruiting
Kaiser Permanente-Walnut Creek
Walnut Creek, California, United States
Jennifer M. Suga
Recruiting
Uchealth University of Colorado Hospital
Aurora, Colorado, United States
Daniel W. Bowles
Recruiting
Uchealth Highlands Ranch Hospital
Highlands Ranch, Colorado, United States
Daniel W. Bowles
Recruiting
Miami Cancer Institute
Miami, Florida, United States
Noah S. Kalman
Recruiting
Emory University Hospital Midtown
Atlanta, Georgia, United States
Conor E. Steuer
Recruiting
Kaiser Permanente Moanalua Medical Center
Honolulu, Hawaii, United States
Jennifer M. Suga
Recruiting
Saint Luke'S Cancer Institute - Boise
Boise, Idaho, United States
Dan S. Zuckerman
Recruiting
Saint Luke'S Cancer Institute - Fruitland
Fruitland, Idaho, United States
Dan S. Zuckerman
Recruiting
Saint Luke'S Cancer Institute - Meridian
Meridian, Idaho, United States
Dan S. Zuckerman
Recruiting
Saint Luke'S Cancer Institute - Nampa
Nampa, Idaho, United States
Dan S. Zuckerman
Recruiting
Saint Luke'S Cancer Institute - Twin Falls
Twin Falls, Idaho, United States
Dan S. Zuckerman
Recruiting
Carle at the Riverfront
Danville, Illinois, United States
Prem Sobti
Recruiting
Carle Physician Group-Effingham
Effingham, Illinois, United States
Prem Sobti
Recruiting
Carle Physician Group-Mattoon/charleston
Mattoon, Illinois, United States
Prem Sobti
Recruiting
Memorial Hospital East
Shiloh, Illinois, United States
Christine Auberle
Recruiting
Carle Cancer Center
Urbana, Illinois, United States
Prem Sobti
Recruiting
Mcfarland Clinic - Ames
Ames, Iowa, United States
Active, not recruiting

112 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 3 Mar 2023
Primary completion: 31 Jul 2028
Completion: 31 Jul 2028
Last update posted: 25 Jun 2026
Registered enrollment: 146
Registry id: NCT05408845

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.