Clinical trialNCT05886049RecruitingPhase 1Interventional

A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

SponsorNational Cancer Institute (NCI)Enrollment38Acute Myeloid LeukemiaAcute Myeloid Leukemia With KMT2A RearrangementAcute Myeloid Leukemia With NPM1 MutationSecondary Acute Myeloid Leukemia

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alice S Mims
Ohio State University Comprehensive Cancer Center LAO
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

22 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Uc Irvine Health/chao Family Comprehensive Cancer Center
Orange, California, United States
Kiran Naqvi
Recruiting
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Suspended
Um Sylvester Comprehensive Cancer Center at Aventura
Aventura, Florida, United States
Sangeetha Venugopal
Recruiting
Um Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, United States
Sangeetha Venugopal
Recruiting
Um Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, United States
Sangeetha Venugopal
Recruiting
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States
Sangeetha Venugopal
Recruiting
Um Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, United States
Sangeetha Venugopal
Recruiting
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States
Olatoyosi M. Odenike
Recruiting
University of Kansas Clinical Research Center
Fairway, Kansas, United States
Jesus Gonzalez Lugo
Recruiting
University of Kansas Cancer Center
Kansas City, Kansas, United States
Jesus Gonzalez Lugo
Recruiting
University of Kansas Hospital-Indian Creek Campus
Overland Park, Kansas, United States
Jesus Gonzalez Lugo
Recruiting
University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas, United States
Jesus Gonzalez Lugo
Recruiting
University of Maryland/greenebaum Cancer Center
Baltimore, Maryland, United States
Vu H. Duong
Recruiting
Unc Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, United States
Joshua F. Zeidner
Recruiting
Carolinas Medical Center/levine Cancer Institute
Charlotte, North Carolina, United States
Brittany K. Ragon
Recruiting
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Matthew J. Wieduwilt
Recruiting
University of Cincinnati Cancer Center-Uc Medical Center
Cincinnati, Ohio, United States
Emily K. Curran
Recruiting
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States
Alice S. Mims
Recruiting
University of Cincinnati Cancer Center-West Chester
West Chester, Ohio, United States
Emily K. Curran
Recruiting
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
Mohamad Khawandanah
Recruiting
Huntsman Cancer Institute/university of Utah
Salt Lake City, Utah, United States
Paul J. Shami
Recruiting
University of Virginia Cancer Center
Charlottesville, Virginia, United States
Active, not recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 Jun 2024
Primary completion: 31 Dec 2027
Completion: 31 Dec 2027
Last update posted: 17 Jun 2026
Registered enrollment: 38
Registry id: NCT05886049

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.