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Clinical trialNCT06161974RecruitingPhase 2Interventional

Study of Olutasidenib and Temozolomide in HGG

SponsorRigel PharmaceuticalsEnrollment60AstrocytomaAstrocytoma, Grade IIIAstrocytoma, Grade IVDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantHigh Grade Glioma+13 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

20 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Sydney Children'S Hospital

    Randwick, New South Wales, Australia

    Recruiting
  • Queensland Children'S Hospital

    South Brisbane, Queensland, Australia

    Not, yet, recruiting
  • Perth Children'S Hospital

    Perth, Western Australia, Australia

    Recruiting
Canada
  • the Hospital for Sick Children (sickkids)

    Toronto, Ontario, Canada

    Not, yet, recruiting
  • Montreal Children'S Hospital

    Montreal, Quebec, Canada

    Not, yet, recruiting
Germany
  • Hopp Children'S Cancer Center at Nct Heidelberg (kitz)

    Heidelberg, Baden-Wurttemberg, Germany

    Not, yet, recruiting
Netherlands
  • Princess Máxima Center

    Utrecht, Netherlands

    Not, yet, recruiting
New Zealand
  • Starship Children'S Hospital

    Auckland, Grafton, New Zealand

    Not, yet, recruiting
United Kingdom
  • Great Ormond Street Hospital

    London, United Kingdom

    Not, yet, recruiting
United States
  • Children'S Hospital Colorado

    Aurora, Colorado, United States

    Not, yet, recruiting
  • Children'S National Medical Center

    Washington D.C., District of Columbia, United States

    Not, yet, recruiting
  • University of Miami Hospital and Clinics

    Miami, Florida, United States

    Recruiting
  • Ann & Robert H. Lurie Children'S Hospital of Chicago

    Chicago, Illinois, United States

    Recruiting
  • Susan Chi

    Boston, Massachusetts, United States

    Not, yet, recruiting
  • Duke University Health System

    Durham, North Carolina, United States

    Recruiting
  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

    Recruiting
  • Nationwide Children'S Hospital

    Columbus, Ohio, United States

    Recruiting
  • Children'S Hospital of Philadelphia

    Philadelphia, Pennsylvania, United States

    Not, yet, recruiting
  • Texas Children'S Hospital

    Houston, Texas, United States

    Not, yet, recruiting
  • Seattle Children'S Hospital

    Seattle, Washington, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Feb 2025
Primary completion
30 Jun 2029
Completion
30 Jun 2035
Last update posted
12 Jun 2026
Registered enrollment
60
Registry id
NCT06161974

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.